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间接血凝反应(LH)——检测水痘-带状疱疹(VZ)病毒回忆抗体的首选方法。

Indirect haemagglutination reaction (LH)-the method of choice for the detection of anamnestic antibodies to varicella - zoster (VZ) virus.

作者信息

Trlifajová J, Ryba M, Jelĭnek J

出版信息

J Hyg Epidemiol Microbiol Immunol. 1976;20(1):101-6.

PMID:177705
Abstract

The method of indirect haemagglutination is a sensitive quantitative serological reaction for the detection of anamnestic titres of VZ antibodies. The curve obtained by the examination of a representative population sample has shown that the occurrence of VZ antibodies increases with the age so that 60% of children of under-school age and 90% of 15-year-old children have antibodies to varicella-zoster virus. In adult age groups, seropositivity ranges between 90--100%. The incidence and level of antibodies are identical in both sexes and do not decrease in old age groups. The mean titre of indirect haemagglutinating antibodies was 1 : 128.

摘要

间接血凝法是一种用于检测水痘带状疱疹(VZ)抗体回忆反应滴度的敏感定量血清学反应。对代表性人群样本进行检测所得到的曲线表明,VZ抗体的出现率随年龄增长而增加,因此60%的学龄前儿童和90%的15岁儿童具有水痘带状疱疹病毒抗体。在成年人年龄组中,血清阳性率在90%至100%之间。两性的抗体发生率和水平相同,且在老年组中也不降低。间接血凝抗体的平均滴度为1:128。

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