Barshteĭn Iu A, Paliĭ G K, Persidskiĭ Iu V, Ben'iaminov V O, Pushkar' M S
Biull Eksp Biol Med. 1991 Dec;112(12):657-9.
Dynamic investigation of several immunologic data and complex morphologic study of the thymus of rats fed for a long time (6 months) by very low doses of herbicide simazine have been carried out. Chronic simazine treatment resulted in the development of the secondary immunodeficient state with the damage of T lymphocytes. The morphologic signs of this process were the disarray in thymus structure (dystrophic changes and intercellular contact break of nurse cells, sclerosis of microvessel walls and stromal elements), severe decrease of the T lymphocyte number in peripheral blood, inhibition of phagocytosis reaction of neutrophils.
对长期（6个月）喂食极低剂量除草剂西玛津的大鼠的多种免疫数据进行了动态研究，并对其胸腺进行了复杂的形态学研究。长期使用西玛津治疗导致继发性免疫缺陷状态的发展，伴有T淋巴细胞损伤。这一过程的形态学特征为胸腺结构紊乱（滋养细胞营养不良性改变及细胞间接触中断、微血管壁和基质成分硬化）、外周血T淋巴细胞数量严重减少、中性粒细胞吞噬反应受到抑制。
