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[在长期接触除草剂利谷隆的背景下对局部葡萄球菌感染的免疫学和形态学研究]

[An immunological and morphological study of focal staphylococcal infection against a background of long-term exposure to the herbicide linuron].

作者信息

Barshteĭn Iu A, Paliĭ G K, Persidskiĭ Iu V, Ben'iaminov V O

出版信息

Mikrobiol Zh (1978). 1990 Sep-Oct;52(5):52-9.

PMID:2084508
Abstract

Small doses of long-term injection of herbicide linuron causes the appearance of secondary immunodeficiency. It is manifested in histological and ultrastructural determination of thymus, severe suppression of immunological indices. Epithelial nurse-cells damage takes place in thymus, the contacts between epithelial cells are destroyed, the reforming of microvessels (their endothelium) occurs which causes the deterioration of vessels penetration and the growth of connective tissue. Against this background a more rapid development of experimental staphylococcus abscesses is observed in animals, the reparation phase being absent.

摘要

长期注射小剂量除草剂利谷隆会导致继发性免疫缺陷的出现。这在胸腺的组织学和超微结构测定中表现为免疫指标的严重抑制。胸腺中上皮滋养细胞受损,上皮细胞之间的接触被破坏,微血管(其内皮)发生重塑,导致血管通透性恶化和结缔组织生长。在此背景下,观察到动物实验性葡萄球菌脓肿发展更快,且不存在修复期。

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