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脂质微管:分子工程结构的范例。

Lipid tubules: a paradigm for molecularly engineered structures.

作者信息

Schnur J M

出版信息

Science. 1993 Dec 10;262(5140):1669-76. doi: 10.1126/science.262.5140.1669.

Abstract

The use of molecular self-assembly to fabricate microstructures suitable for advanced material development is described. Templating techniques that transform biomolecular self-assemblies into rugged and stable nano- and microstructures are described. By using a lipid-based microcylinder (tubule) as a paradigm, the path followed from research and development to emerging technological applications is detailed. This process includes modification of the lipid molecular structure, the formation and subsequent characterization of cylindrical microstructures, the use of these structures as templates for metallization, and the characterization and assessment of these hollow metal microcylinders for several potential applications.

摘要

本文描述了利用分子自组装来制造适用于先进材料开发的微观结构。阐述了将生物分子自组装转化为坚固且稳定的纳米和微观结构的模板技术。以基于脂质的微圆柱体(微管)为例,详细介绍了从研发到新兴技术应用所遵循的路径。这个过程包括脂质分子结构的修饰、圆柱形微观结构的形成及后续表征、将这些结构用作金属化模板,以及对这些空心金属微圆柱体在多种潜在应用中的表征和评估。

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