Baulieu E E
INSERM U 33 Lab Hormones, Bicêtre, France.
Endocrinol Metab Clin North Am. 1991 Dec;20(4):873-91.
The cellular and molecular mechanism of RU486, a steroid hormone antagonist, is discussed in detail. Principally, RU486 opposes the action of two types of hormones: progesterone and glucocorticosteroids. The clinical applications are also described, as well as the future outlook.