Vavilov General Genetics Institute, U.S.S.R. Academy of Sciences, Moscow.
Genetica. 1991;85(1):79-90. doi: 10.1007/BF00056109.
Three approaches to the estimation of the role of balancing selection in maintaining allozyme polymorphism are considered: 1) Analysis of the stationary distributions of allelic frequencies in a native subdivided population; 2) Comparison of the genotypic distributions at the early and late developmental stages in successive generations of the same population; 3) Analysis of the 'joint' variability of monogenic and polygenic traits. The conclusion is drawn that allozyme polymorphism must not be regarded as a transient phase of molecular evolution but as its stationary phase. The mechanisms responsible for supporting such stability are discussed.
1）分析本地细分群体中等位基因频率的平稳分布；2）比较同一群体连续世代发育早期和晚期的基因型分布；3）分析单基因和多基因性状的“联合”变异性。得出的结论是，等位酶多态性不应被视为分子进化的过渡阶段，而应被视为其稳定阶段。文中还讨论了维持这种稳定性的机制。
