Rasmussen Susanne R, Thomsen Janus L, Kilsmark Jannie, Hvenegaard Anne, Engberg Marianne, Lauritzen Torsten, Søgaard Jes
DSI Danish Institute for Health Services Research, Copenhagen, Denmark.
Scand J Public Health. 2007;35(4):365-72. doi: 10.1080/14034940701219642.
The intention was to investigate whether preventive health checks and health discussions are cost effective.
In a randomized trial the authors compared two intervention groups (A and B) and one control group. In 1991 2,000 30- to 49-year-old persons were invited and those who accepted were randomized. Both intervention groups were offered a broad (multiphasic) screening including cardiovascular risk and a personal letter including screening results and advice on healthy living. Individuals in group A could contact their family physician for a normal consultation whereas group B were given fixed appointments for health consultations. The follow-up period was six years. Analysis was carried out on the "intention to treat" principle. Outcome parameters were life years gained, and direct and total health costs (including productivity costs), discounted by 3% annually. Costs were based on register data. Univariate sensitivity analysis was carried out.
Both intervention groups have significantly better life expectancy than the control group (no intervention). Group B and (A) significantly gain 0.14 (0.08) life years more than the control group. There were no differences in average direct (3,255 euro (3,703 euro) versus 4,186 euro) and total costs (10,409 euro (9,399 euro) versus 10,667 euro). The effect in group B is, however, better than in group A with no significant differences in costs. The results are insensitive to a range of assumptions regarding costs, effects, and discount rates.
Preventive health screening and consultation in primary care in 30- to 49-year-olds produce significantly better life expectancy without extra direct and total costs over a six-year follow-up period.
旨在研究预防性健康检查和健康讨论是否具有成本效益。
在一项随机试验中,作者比较了两个干预组(A组和B组)和一个对照组。1991年,邀请了2000名30至49岁的人群,接受邀请者被随机分组。两个干预组都接受了包括心血管风险在内的全面(多阶段)筛查,并收到一封包含筛查结果和健康生活建议的个人信件。A组的个体可以联系他们的家庭医生进行常规咨询,而B组则被安排了固定的健康咨询预约。随访期为六年。分析按照“意向性分析”原则进行。结果参数为获得的生命年数,以及直接和总健康成本(包括生产力成本),每年按3%进行贴现。成本基于登记数据。进行了单因素敏感性分析。
两个干预组的预期寿命均显著高于对照组(无干预)。B组和A组比对照组显著多获得0.14(0.08)个生命年。平均直接成本(3255欧元(3703欧元)对4186欧元)和总成本(10409欧元(9399欧元)对10667欧元)没有差异。然而,B组的效果优于A组,成本没有显著差异。结果对一系列关于成本、效果和贴现率的假设不敏感。
在30至49岁人群的初级保健中进行预防性健康筛查和咨询,在六年的随访期内可显著提高预期寿命,且不会产生额外的直接和总成本。