Ward R S, Tuckett R P
Intermountain Burn Center, University of Utah Health Sciences Center, Salt Lake City.
J Burn Care Rehabil. 1991 Nov-Dec;12(6):569-75. doi: 10.1097/00004630-199111000-00013.
Decreased cutaneous sensation is common after burn injury. This study was designed to quantitate threshold sensory loss with the use of a microcomputer-based sensory testing device that generated precisely controlled stimuli. Threshold evaluations of two-point discrimination, pinprick, warming, touch, and vibration were performed on patients with burns (n = 16) and on control subjects (n = 42). All threshold measures in patients with burns were elevated above those for control subjects; threshold measures that reached statistical significance were two-point discrimination, warming, touch, and vibration. Unburned sites on patients with burns had higher thresholds than sites on control subjects, though only vibration was significant. A significant correlation was found between the magnitude of touch and vibration thresholds in control subjects, but there was no similar correlation found in patients with burns. When controls for age were applied, touch and vibration thresholds remained significantly elevated above control levels, and decreases in significance for two-point discrimination and warming were noted. It was concluded that sensory function is reduced in patients with burns. Alternative mechanisms that may have caused the sensory changes were discussed.
烧伤后皮肤感觉减退很常见。本研究旨在使用基于微型计算机的感觉测试设备来定量阈值感觉丧失，该设备能产生精确控制的刺激。对烧伤患者（n = 16）和对照受试者（n = 42）进行了两点辨别觉、针刺觉、温热觉、触觉和振动觉的阈值评估。烧伤患者的所有阈值测量值均高于对照受试者；达到统计学显著性的阈值测量是两点辨别觉、温热觉、触觉和振动觉。烧伤患者的未烧伤部位阈值高于对照受试者的相应部位，不过只有振动觉具有显著性。在对照受试者中，触觉和振动觉阈值大小之间存在显著相关性，但在烧伤患者中未发现类似相关性。当对年龄进行校正时，触觉和振动觉阈值仍显著高于对照水平，且两点辨别觉和温热觉的显著性有所降低。得出的结论是，烧伤患者的感觉功能降低。讨论了可能导致感觉变化的其他机制。
