Wilson M C, Barr C C, Gamel J W, Cyrus J, Lynch T N
Department of Ophthalmology and Visual Sciences, Kentucky Lions Eye Research Institute, Louisville.
J Diabet Complications. 1991 Oct-Dec;5(4):221-4. doi: 10.1016/0891-6632(91)90080-9.
Medical practitioners often have difficulty in assessing the presence or severity of diabetic retinopathy. The tourniquet test is a method of assessing diabetic capillary fragility that has been felt to reliably correlate with background and proliferative diabetic retinopathy. We studied 100 consecutive diabetic patients and 50 age-matched controls in a masked fashion, using fundus photographs and fluorescein angiography to correlate the amount of capillary fragility with the presence and severity of background and proliferative diabetic retinopathy. Although the severity of diabetic capillary fragility did correlate with the presence and severity of diabetic retinopathy (p less than 0.001), this test was not as good an indicator of diabetic retinopathy as were other risk factors such as duration of diabetes (p much less than 0.001). The tourniquet test is unreliable in predicting the presence or severity of diabetic retinopathy because of its high false negative response rate.
医学从业者在评估糖尿病视网膜病变的存在或严重程度时常常遇到困难。止血带试验是一种评估糖尿病毛细血管脆性的方法，人们认为它与背景性和增殖性糖尿病视网膜病变有可靠的相关性。我们以盲法研究了100例连续的糖尿病患者和50例年龄匹配的对照者，使用眼底照片和荧光素血管造影来关联毛细血管脆性的程度与背景性和增殖性糖尿病视网膜病变的存在及严重程度。尽管糖尿病毛细血管脆性的严重程度确实与糖尿病视网膜病变的存在及严重程度相关（p小于0.001），但该试验作为糖尿病视网膜病变的指标并不如糖尿病病程等其他危险因素（p远小于0.001）。由于其高假阴性反应率，止血带试验在预测糖尿病视网膜病变的存在或严重程度方面并不可靠。
