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近期诊断为糖尿病患者的糖尿病视网膜病变患病率

Prevalence of diabetic retinopathy in patients with recently diagnosed diabetes mellitus.

作者信息

Lee Ka Man Carmen, Sum Wing Man Rita

机构信息

Integrative Community Health Centre, School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, China.

出版信息

Clin Exp Optom. 2011 Jul;94(4):371-5. doi: 10.1111/j.1444-0938.2010.00574.x. Epub 2011 Feb 16.

Abstract

BACKGROUND

The severity of diabetic retinopathy is well known to have a close association with the duration of diabetes mellitus. Patients with recently diagnosed diabetes should have adequate eye examinations to eliminate the possibility of diabetic retinopathy being present because there is no accurate means of determining the duration of the disease. The prevalence of diabetic retinopathy in type 2 diabetic patients with known duration up to one year was investigated in the present study.

METHODS

A centre for diabetic retinopathy screening was set up in a community in Hong Kong. The screening procedures included history taking, visual acuity measurement, anterior ocular health assessment and retinal examination by fundus photography. Fundus photographs were taken in nine different positions of gaze through natural or dilated pupils. Using the criteria recommended by the American Optometric Association the retinopathy was graded in severity. 'Recently diagnosed diabetes mellitus' was defined as having diabetes diagnosed by a physician within the previous year.

RESULTS

A total of 12,112 patients having their first visits to the centre were recruited from 2006 to 2009. Among them, 3,510 patients had recently diagnosed diabetes. The mean age of patients was 59.5 years. The prevalence of diabetic retinopathy was 18.2 per cent (639 patients) among the recently diagnosed diabetic patients. Most of the patients had mild non-proliferative diabetic retinopathy. In these 639 patients, approximately seven per cent had sight-threatening retinopathy that included significant macular oedema, all of whom required monitoring. The presence of hypertension or smoking was not significantly associated with the prevalence of diabetic retinopathy in recently diagnosed diabetic patients.

CONCLUSIONS

Screening for diabetic retinopathy is important for newly diagnosed diabetic patients. In Hong Kong, the prevalence of diabetic retinopathy was alarmingly high and some patients had already developed sight-threatening retinopathy that included macular oedema. Most of them had no symptoms until the retinopathy progressed and they developed macular oedema. A systematic screening program in the community is needed for early detection and to reduce blindness in diabetic patients.

摘要

背景

糖尿病视网膜病变的严重程度与糖尿病病程密切相关,这是众所周知的。近期确诊糖尿病的患者应进行充分的眼部检查,以排除糖尿病视网膜病变的可能性,因为目前尚无准确方法确定该病的病程。本研究调查了病程已知达一年的2型糖尿病患者中糖尿病视网膜病变的患病率。

方法

在香港的一个社区设立了糖尿病视网膜病变筛查中心。筛查程序包括病史采集、视力测量、眼前部健康评估以及通过眼底照相进行视网膜检查。通过自然瞳孔或散瞳在九个不同注视位置拍摄眼底照片。根据美国验光协会推荐的标准对视网膜病变的严重程度进行分级。“近期确诊的糖尿病”定义为在前一年由医生确诊为糖尿病。

结果

2006年至2009年共招募了12112名首次到该中心就诊的患者。其中,3510名患者为近期确诊的糖尿病患者。患者的平均年龄为59.5岁。近期确诊的糖尿病患者中糖尿病视网膜病变的患病率为18.2%(639例患者)。大多数患者患有轻度非增殖性糖尿病视网膜病变。在这639例患者中,约7%患有威胁视力的视网膜病变,包括显著的黄斑水肿,所有这些患者都需要进行监测。高血压或吸烟的存在与近期确诊的糖尿病患者中糖尿病视网膜病变的患病率无显著相关性。

结论

对新确诊的糖尿病患者进行糖尿病视网膜病变筛查很重要。在香港,糖尿病视网膜病变的患病率高得惊人,一些患者已经出现了包括黄斑水肿在内的威胁视力的视网膜病变。他们中的大多数在视网膜病变进展并出现黄斑水肿之前没有症状。社区需要一个系统的筛查项目,以便早期发现并减少糖尿病患者的失明。

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