他莫昔芬治疗的乳腺癌患者中的子宫内膜癌

Endometrial carcinoma in tamoxifen-treated breast cancer patients.

作者信息

Spinelli G, Bardazzi N, Citernesi A, Fontanarosa M, Curiel P

机构信息

Department of Obstetrics and Gynecology, City Hospital, Prato, Italy.

出版信息

J Chemother. 1991 Aug;3(4):267-70. doi: 10.1080/1120009x.1991.11739104.

DOI:10.1080/1120009x.1991.11739104

PMID:1779263

Abstract

Tamoxifen is an important agent for the treatment of breast cancer. Occasionally the drug, which is an antiestrogen, has agonistic estrogenic activity. The authors describe three new cases of endometrial carcinoma developing in breast cancer patients taking tamoxifen and stress the necessity of carefully monitoring the uterine cavity under tamoxifen treatment.

摘要

他莫昔芬是治疗乳腺癌的一种重要药物。这种抗雌激素药物偶尔会有雌激素激动活性。作者描述了3例服用他莫昔芬的乳腺癌患者发生子宫内膜癌的新病例，并强调在他莫昔芬治疗期间仔细监测子宫腔的必要性。