Segna R A, Dottino P R, Deligdisch L, Cohen C J
Department of Obstetrics, Gynecology and Reproductive Science, Mount Sinai School of Medicine, New York, NY.
Mt Sinai J Med. 1992 Oct;59(5):416-8.
Tamoxifen is a nonsteroidal antiestrogen employed frequently in the treatment of breast cancer. An association between this drug and endometrial neoplasia has been reported. We report on 11 postmenopausal women with breast cancer who developed endometrial cancer while undergoing tamoxifen therapy and recommend aggressive investigation of vaginal bleeding in all women being treated with this agent.
他莫昔芬是一种非甾体类抗雌激素药物，常用于治疗乳腺癌。已有报道称这种药物与子宫内膜肿瘤之间存在关联。我们报告了11例绝经后乳腺癌患者，她们在接受他莫昔芬治疗期间患上了子宫内膜癌，并建议对所有接受该药物治疗的女性出现的阴道出血进行积极检查。
