Ojima M, Hasegawa E, Ogawa T
Department of Ophthalmology, Kagawa Medical School, Japan.
Jpn J Ophthalmol. 1991;35(2):188-93.
The changes in the choroidal vascular resistance after carotid artery ligation were compared with those in the cerebrum and the inferior rectus muscle by evaluating the changes in the blood flow by the hydrogen clearance method. Ligation of the carotid artery produced little change in the ipsilateral cerebral blood flow, but decreased the choroidal blood flow by 16-24% and the blood flow of the inferior rectus muscle by 34-40%. Although the reduction in the arterial pressure in these organs was the same, the responses of the blood flows to the changes in the arterial pressure were different. This suggests that autoregulatory capability varies from organ to organ. It is important to study the pathogenesis of carotid artery occlusion giving special consideration to these differences among the autoregulatory capabilities of various organs.
通过氢清除法评估血流量变化，比较颈动脉结扎后脉络膜血管阻力的变化与大脑及下直肌的变化。颈动脉结扎对同侧脑血流量影响不大，但脉络膜血流量减少了16% - 24%，下直肌血流量减少了34% - 40%。尽管这些器官的动脉压下降幅度相同，但血流量对动脉压变化的反应却不同。这表明不同器官的自身调节能力存在差异。在研究颈动脉闭塞的发病机制时，特别考虑不同器官自身调节能力的这些差异非常重要。
