怀孕和哺乳期小鼠乳腺中的环核苷酸、腺苷酸环化酶和环磷酸腺苷磷酸二酯酶
Cyclic nucleotides, adenylate cyclase, and cyclic AMP phosphodiesterase in mammary glands from pregnant and lactating mice.
作者信息
Rillema J A
出版信息
Proc Soc Exp Biol Med. 1976 Apr;151(4):748-51. doi: 10.3181/00379727-151-39299.
PMID:177987
Abstract
In the mammary glands of mice, levels of cyclic AMP increased during pregnancy and then fell precipitously following parturition. In contrast, levels of cyclic GMP fell during the gestation period and then rose rapidly during the early days of lactation. Adenylate cyclase and cyclic AMP hohsphodiesterase activities were elevated during the pregnancy and lactation periods.
摘要
在小鼠的乳腺中，环磷酸腺苷（cAMP）水平在怀孕期间升高，然后在分娩后急剧下降。相比之下，环磷酸鸟苷（cGMP）水平在妊娠期下降，然后在泌乳早期迅速上升。腺苷酸环化酶和环磷酸腺苷磷酸二酯酶的活性在怀孕和哺乳期升高。
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