Sahib A Kader, Sahu Sujit Kumar, Reddy K N
Department of Cardiology, Vijaya Heart Foundation, Chennai 600026.
J Indian Med Assoc. 2007 Jan;105(1):25-8.
Prediabetes occurs due to two basic defects--insulin resistance and/or beta-cell failure. An observation suggested that insulin resistance may be associated with essential hypertension. There are some thoughts to favour the argument that insulin resistant Individuals are at a higher risk to develop hypertension as compared to insulin sensitive individuals. Some pathophysiological causes which have been commonly observed and hypothesised are narrated in this article. Management of hypertension in prediabetes should include antihypertensives and therapeutic lifestyle modification. To manage hypertension in prediabetes one should think for dietary modification, reduced salt intake, physical activity, smoking cessation, use of statins and antihypertensives.
糖尿病前期的发生是由于两个基本缺陷——胰岛素抵抗和/或β细胞功能衰竭。一项观察表明，胰岛素抵抗可能与原发性高血压有关。有一些观点支持这样的论点，即与胰岛素敏感个体相比，胰岛素抵抗个体患高血压的风险更高。本文叙述了一些常见的和假设的病理生理原因。糖尿病前期高血压的管理应包括抗高血压药物治疗和治疗性生活方式改变。为了管理糖尿病前期的高血压，应该考虑饮食调整、减少盐摄入、体育锻炼、戒烟、使用他汀类药物和抗高血压药物。
