Wedding U, Koch A, Röhrig B, Pientka L, Sauer H, Höffken K, Maurer I
Department of Haematology and Medical Oncology, Friedrich-Schiller-University, Jena, Germany.
Ann Oncol. 2007 Nov;18(11):1875-81. doi: 10.1093/annonc/mdm353. Epub 2007 Sep 5.
Depressive symptoms are a major complaint reported by cancer patients. Somatic and affective symptoms can contribute to depression.
We investigated the prevalence of somatic and affective depressive symptoms with the Beck Depression Inventory (BDI) in 213 hospitalized cancer patients prior to the start of chemotherapy.
Seventeen of 213 patients (8%) were screened positive for major depression; 40 (19%) had mild to moderate depressive symptoms. The corresponding figures for somatic and affective symptoms were 33.3% and 2.8% in the patients with major depression and 23.0% and 8.0% in those with mild to moderate depressive symptoms. Female patients, patients with solid tumour and those with functional limitations had significantly higher mean scores. All differences were related to higher scores in somatic and not in affective items.
Most alterations in the BDI in cancer patients are related to somatic and not to affective symptoms and may be attributed not to depression but to severity of the underlying disease.
抑郁症状是癌症患者报告的主要主诉。躯体症状和情感症状可导致抑郁。
我们在213例住院癌症患者化疗开始前,使用贝克抑郁量表(BDI)调查了躯体和情感抑郁症状的患病率。
213例患者中有17例(8%)被筛查出重度抑郁阳性;40例(19%)有轻度至中度抑郁症状。重度抑郁患者中躯体和情感症状的相应比例分别为33.3%和2.8%,轻度至中度抑郁症状患者中分别为23.0%和8.0%。女性患者、实体瘤患者和有功能受限的患者平均得分显著更高。所有差异均与躯体项目得分较高有关,而非情感项目得分较高。
癌症患者BDI的大多数变化与躯体症状而非情感症状有关,可能不是归因于抑郁,而是归因于基础疾病的严重程度。