Bourgeois P, Cywiner-Golenzer C, Lessana-Leibowitch M, Kahn M F, de Sèze S
Rev Rhum Mal Osteoartic. 1976 Feb;43(2):85-91.
The authors have observed 3 cases of pure scleroderma and one case of scleroderma in which tendinous or subcutaneous nodular structures were present. To the author's knowledge, such nodules have never been described previously in cases of scleroderma. Their site and their histology identifies them as "rheumatoid" nodules and at the same time provides other valuable information. Scleroderma is thus, together with rheumatoid polyarthritis and lupus erythematosus, one of the possible causes of nodule formation, and the authors put forward the hypothesis that these nodules might represent one of the first lesions of the Thibierge and Weissenbach syndrome.
作者观察到3例纯硬皮病和1例伴有肌腱或皮下结节状结构的硬皮病。据作者所知,此前硬皮病病例中从未描述过此类结节。它们的位置和组织学特征将其鉴定为“类风湿性”结节,同时还提供了其他有价值的信息。因此,硬皮病与类风湿性多关节炎和红斑狼疮一样,是结节形成的可能原因之一,作者提出假说,这些结节可能代表蒂比耶热和魏森巴赫综合征的首批病变之一。