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来自急性中耳炎患儿的配对中耳和咽部分离的非分型流感嗜血杆菌的遗传多样性。

Genetic diversity of paired middle-ear and pharyngeal nontypeable Haemophilus influenzae isolates from children with acute otitis media.

作者信息

Berrens Zachary J, Marrs Carl F, Pettigrew Melinda M, Sandstedt Sara A, Patel Mayuri, Gilsdorf Janet R

机构信息

University of Michigan, Department of Pediatrics and Communicable Diseases, L2224 Women's Hospital, Ann Arbor, MI 48109-5244, USA.

出版信息

J Clin Microbiol. 2007 Nov;45(11):3764-7. doi: 10.1128/JCM.00964-07. Epub 2007 Sep 5.

DOI:10.1128/JCM.00964-07
PMID:17804648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2168485/
Abstract

Pulsed-field gel electrophoresis was used to determine genetic diversities of multiple nontypeable Haemophilus influenzae isolates from throat and ear specimens of eight children with otitis media. From five children, all ear and throat isolates were identical. The bacterial populations in these specimens showed less diversity than populations in throat isolates of healthy children.

摘要

采用脉冲场凝胶电泳法来测定从8名中耳炎患儿的咽喉和耳部标本中分离出的多种不可分型流感嗜血杆菌菌株的遗传多样性。在5名儿童中，所有耳部和咽喉分离株均相同。这些标本中的细菌群体显示出的多样性低于健康儿童咽喉分离株中的细菌群体。

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本文引用的文献

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J Infect Dis. 2007 Jan 1;195(1):81-9. doi: 10.1086/509824. Epub 2006 Nov 27.
2
Presence of copper- and zinc-containing superoxide dismutase in commensal Haemophilus haemolyticus isolates can be used as a marker to discriminate them from nontypeable H. influenzae isolates.共生溶血嗜血杆菌分离株中含铜和锌的超氧化物歧化酶的存在可作为将它们与不可分型流感嗜血杆菌分离株区分开来的标志物。
J Clin Microbiol. 2006 Nov;44(11):4222-6. doi: 10.1128/JCM.01376-06. Epub 2006 Sep 20.
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Investigation about the homogeneity of nasopharyngeal microflora at the different location of nasopharynx of children with acute otitis media.急性中耳炎患儿鼻咽部不同位置微生物群同质性的研究
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