Sacco M, Rotta P, Rampino M
Istituto di Radiologia, Università, Torino.
Radiol Med. 1991 Nov;82(5):658-63.
From January 1980 through December 1987, 128 endometrial carcinomas were treated with combined irradiation and surgery (101 cases) or with radiotherapy alone (27 patients). Mean follow-up was 5 years (range: 2-9). Actuarial disease-free (DF) survival (according to the Kaplan and Meyer method) was 86% for T1-T2 patients, 50% for T3 cases and 35% for T4. Recurrence rate was 20% (26 patients): 9 had local recurrences, 9 nodal relapses, and 8 distant metastases. Overall side-effects were observed in only 7/128 patients (5.4%): they were grade I in 6 cases and grade II in 1. The evaluation of the prognostic factors confirms the importance of: stage (disease-free survival at 5 years: 86% for T1-T2 versus 50-35% for T3-T4); uterus size in stage T1 (DF survival at 5 years: 90% for T1A versus 70% for T1B); grading (DF survival at 5 years: 92, 87, 62% for G1, G2, G3, respectively). Myometrial infiltration seems to have no prognostic value.
从1980年1月至1987年12月，128例子宫内膜癌患者接受了放疗与手术联合治疗（101例）或单纯放疗（27例）。平均随访时间为5年（范围：2 - 9年）。根据Kaplan和Meyer方法计算，T1 - T2期患者的无病（DF）生存率为86%，T3期为50%，T4期为35%。复发率为20%（26例患者）：9例为局部复发，9例为淋巴结转移，8例为远处转移。仅7/128例患者（5.4%）观察到总体副作用：6例为I级，1例为II级。对预后因素的评估证实了以下因素的重要性：分期（5年无病生存率：T1 - T2期为86%，而T3 - T4期为50% - 35%）；T1期的子宫大小（5年无病生存率：T1A期为90%，T1B期为70%）；分级（5年无病生存率：G1、G2、G3级分别为92%、87%、62%）。肌层浸润似乎没有预后价值。
