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Lophyrotomin, a new toxic octapeptide from the larvae of sawfly, Lophyrotoma interrupta.

作者信息

Oelrichs P B, Vallely P J, Macleod J K, Cable J, Kiely D E, Summons R E

出版信息

Lloydia. 1977 Mar-Apr;40(2):209-14.

PMID:17805
Abstract

Lophyrotomin, a new toxic octapeptide, has been isolated from sawfly (Lophyrotoma interrupta) larvae using solvent extraction, dialysis, adsorption on polyamide, ion exchange chromatography on DEAE cellulose and silica gel G chromatography. On the basis of evidence from chemical methods, pmr and mass spectrometry, a partial structure is proposed. Lophyrotomin has an approximate intraperitoneal LD50 of 2 mg/kg for mice.

摘要

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引用本文的文献

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Body distribution of toxic peptides in larvae of a pergid and an argid sawfly species.一种叶蜂和一种三节叶蜂幼虫中毒性肽的身体分布情况。
Naturwissenschaften. 2019 Dec 3;107(1):1. doi: 10.1007/s00114-019-1660-7.
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Endogenous toxins and the coupling of gregariousness to conspicuousness in Argidae and Pergidae sawflies.内源性毒素与 Argidae 和 Pergidae 叶蜂的群居性和显眼性的耦合。
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Venomous and poisonous Australian animals of veterinary importance: a rich source of novel therapeutics.
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Toxic peptides occur frequently in pergid and argid sawfly larvae.有毒肽在叶蜂科和三节叶蜂科锯角叶蜂幼虫中频繁出现。
PLoS One. 2014 Aug 14;9(8):e105301. doi: 10.1371/journal.pone.0105301. eCollection 2014.