Retallick Christopher J, Baker Julien S, Williams Simon R, Whitcombe Dean, Davies Bruce
Division of Health and Exercise Science, University of Glamorgan, Wales, United Kingdom.
Med Sci Sports Exerc. 2007 Sep;39(9):1579-86. doi: 10.1249/mss.0b013e318093f585.
It has been suggested that exercise-induced changes in plasma volume (PV) confound the interpretation of biochemical data obtained during the recovery period from exercise. No studies have sought to assess the effect of short-duration, high-intensity exercise on PV change and plasma lipid and lipoprotein concentrations. The purpose of this study was to compare power profiles, changes in PV, and plasma lipid and lipoprotein concentrations immediately after and 24 h after exercise.
Subjects undertook two 30-s, high-intensity cycle ergometer protocols after optimization of resistive loads calculated from total body mass (TBM) and fat-free mass (FFM). Power output indices were recorded and blood samples were analyzed before, immediately after, and 24 h after exercise.
Peak power outputs were significantly greater in FFM (1020+/-134 vs 953+/-114 W for FFM and TBM, respectively, P<0.05). No differences were found between TBM and FFM for mean power output, fatigue index, or work done. Significant decreases (P<0.05) in PV of 12.0+/-5.7 and 12.3+/-6.7% were recorded immediately after exercise for both TBM and FFM, respectively. At 24 h after exercise, a significant (P<0.05) increase in PV of 4.2+/-10.3% was recorded for TBM only. Significant increases (P<0.01) were recorded for serum triglyceride, cholesterol, HDL cholesterol, and LDL cholesterol immediately after exercise for both TBM and FFM. These increases disappeared when corrected for PV changes, with the exception of LDL cholesterol in TBM, which still displayed a significant increase compared with the preexercise values (2.50+/-0.74 mM (before) vs 2.72+/-0.84 mM (immediately after)).
Our data show that short-duration, high-intensity cycle ergometer exercise tests can induce significant plasma volume decreases in untrained subjects, which may affect the interpretation of bloodborne biochemical parameters.
有人提出，运动引起的血浆容量（PV）变化会混淆运动恢复期所获得生化数据的解读。尚无研究试图评估短时间、高强度运动对PV变化以及血浆脂质和脂蛋白浓度的影响。本研究的目的是比较运动后即刻和运动后24小时的功率曲线、PV变化以及血浆脂质和脂蛋白浓度。
在根据总体重（TBM）和去脂体重（FFM）计算出的阻力负荷优化后，受试者进行了两个30秒的高强度自行车测力计测试。记录功率输出指标，并在运动前、运动后即刻和运动后24小时对血样进行分析。
FFM的峰值功率输出显著更高（FFM和TBM的峰值功率输出分别为1020±134瓦和953±114瓦，P<0.05）。TBM和FFM在平均功率输出、疲劳指数或做功方面未发现差异。运动后即刻，TBM和FFM的PV分别显著降低（P<0.05），降低幅度分别为12.0±5.7%和12.3±6.7%。运动后24小时，仅TBM的PV显著增加（P<0.05），增加幅度为4.2±10.3%。运动后即刻，TBM和FFM的血清甘油三酯、胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇均显著增加（P<0.01）。在校正PV变化后，这些增加消失，但TBM中的低密度脂蛋白胆固醇除外，与运动前值相比仍显示出显著增加（运动前为2.50±0.74毫摩尔，运动后即刻为2.72±0.84毫摩尔）。
我们的数据表明，短时间、高强度的自行车测力计运动测试可导致未经训练的受试者血浆容量显著下降，这可能会影响对血源性生化参数的解读。
