Haettich B, Lebreton C, Prier A, Kaplan G
Service de Rhumatologie, Hôpital Saint-Antoine, Paris.
Rev Rhum Mal Osteoartic. 1991 Nov 30;58(11):803-8.
Osteocondensation of the spine and stress fractures of the appendicular bones are observed under treatment with sodium fluoride or after long-term drinking of Vichy Saint-Yorre spring water. Five patients with a mean total dose of fluoride intake of 24.7 g (9-66) were studied with MR imaging. Two of them had a diffuse osteocondensation; MRI showed a low signal intensity in the vertebrae on T1 and T2-weighted images. MRI was performed in an asymptomatic patient who was being treated with sodium fluoride for 16 months; it revealed a heterogenous low signal intensity in the pelvis and femoral metaphysis. Two patients experienced stress fractures; MRI demonstrated a linear area of very low signal intensity surrounded by an area of decreased signal intensity on T1-weighted images and high signal intensity on T2-weighted images. MRI of fluorosis shows a non specific low signal intensity linked to a densifying image on the standard radiograph or an area of high technetium-99m intake on bone scan.
在使用氟化钠治疗期间或长期饮用维希圣约尔矿泉水后,可观察到脊柱骨硬化和附属骨骼的应力性骨折。对5例平均总氟摄入量为24.7 g(9 - 66 g)的患者进行了磁共振成像(MR成像)研究。其中2例有弥漫性骨硬化;磁共振成像显示在T1加权和T2加权图像上椎体呈低信号强度。对一名接受氟化钠治疗16个月的无症状患者进行了磁共振成像检查;结果显示骨盆和股骨干骺端有不均匀的低信号强度。2例患者发生了应力性骨折;磁共振成像显示在T1加权图像上有一条极低信号强度的线性区域,周围是信号强度降低的区域,在T2加权图像上则为高信号强度区域。氟中毒的磁共振成像表现为与标准X线片上的致密影像或骨扫描上高锝-99m摄取区域相关的非特异性低信号强度。