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[赤道非洲痛风的流行病学和临床特征。关于布拉柴维尔教学医院中心风湿病科随访的60例病例]

[Epidemiological and clinical aspects of gout in equatorial Africa. Apropos of 60 cases followed in the Department of Rheumatology of the Teaching Hospital Center in Brazzaville].

作者信息

Bileckot R, Ntsiba H, Mbongo J A, Sigamong E V, Masson C, Brégeon C

机构信息

Services de Rhumatologie, Centres Hospitaliers Universitaires de Brazzaville, Angers.

出版信息

Rev Rhum Mal Osteoartic. 1991 Dec;58(12):863-7.

PMID:1780667
Abstract

Between December 15, 1988 and November 30, 1990, the application of Rome and New York criteria enabled the diagnosis of 60 cases of gout among patients with arthritis or hyperuricemia seen as out-patients or hospitalised in the Department of Rheumatology of the Brazzavile T.H.G. There were 57 men and 3 women, with a mean age of 51. Gout is the primary form of inflammatory arthropathy in adults in the Congo. Affecting all socio-professional groups, it is diversely associated with obesity, alcoholism, hypertension and diabetes. Initial involvement affects the big toe. Oligo and polyarticular forms predominate because of the absence or delay in specific treatment. This series included 30 per cent of cases of chronic gout. Evidence of renal impairment was found in one third of patients. However, urate lithiasis was absent. Tophi were found preferentially over the elbows. Sickle cell disease was responsible for one case of tophaceous gout. In contrast with the results of studies undertaken before the 1980s, gout is seen to be a common condition in equatorial Africa.

摘要

1988年12月15日至1990年11月30日期间,采用罗马和纽约标准,在布拉柴维尔T.H.G.风湿病科门诊或住院的关节炎或高尿酸血症患者中诊断出60例痛风。其中男性57例,女性3例,平均年龄51岁。痛风是刚果成年人炎症性关节病的主要形式。它影响所有社会职业群体,与肥胖、酗酒、高血压和糖尿病有多种关联。最初受累部位为大脚趾。由于缺乏特异性治疗或治疗延迟,寡关节型和多关节型较为常见。该系列病例中慢性痛风占30%。三分之一的患者有肾功能损害证据。然而,未发现尿酸盐结石。痛风石多见于肘部。镰状细胞病导致1例痛风石性痛风。与20世纪80年代以前的研究结果相比,痛风在赤道非洲被视为一种常见疾病。

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