Tur J A, Prieto R, Grases F
Department of Fundamental Biology and Health Sciences, University of the Balearic Islands, Palma de Mallorca, Spain.
Scand J Urol Nephrol. 1991;25(4):311-4. doi: 10.3109/00365599109024566.
The effects of diet on the formation of calcium oxalate stones were studied in 150-day-old rats by measuring the diuresis, pH, and urinary and blood concentrations of promoting and inhibitory substances. An increase in phosphate (promoting) and magnesium (inhibiting), and a decrease in citrate (inhibiting) and pH were found in the urine of rats fed with a high protein diet. No differences were observed in the plasma concentrations of calcium, magnesium, and phosphate. These results confirm epidemiological and clinical studies in humans that have shown that any diet rich in protein can change the concentrations of these substances in urine.
