Prokubovskiĭ V I, Farber A Ia, Rodionov S V, Safonov M V, Butenko A V
Grud Serdechnososudistaia Khir. 1991 Sep(9):24-30.
Regional thrombolysis was performed in 62 patients with thrombosis of the aorta and arteries of the pelvis and lower extremities. The thrombolytics used were avelysin (20 patients) and celiase (42 patients). Complete lysis of the thrombi was recorded in 49 cases. After successful thrombolytic therapy balloon angioplasty of the revealed stenoses was carried out in 39 patients. After thrombolysis was completed 15 patients underwent various reconstructive operations which failed to produce an effect in 4 patients and the extremity was amputated. The complications of thrombolysis included hematomas at the site of catheterization of the arteries in 5 patients, distal embolism in 7, and an allergic reaction in one patient. The authors appraise the dependence of thrombolysis efficacy on the level, extent, and duration of the thrombotic occlusion.
对62例主动脉及骨盆和下肢动脉血栓形成患者进行了局部溶栓治疗。使用的溶栓剂为阿韦利辛（20例患者）和纤溶酶（42例患者）。49例患者血栓完全溶解。在成功的溶栓治疗后，39例患者对发现的狭窄进行了球囊血管成形术。溶栓完成后，15例患者接受了各种重建手术，其中4例手术无效，肢体被截肢。溶栓的并发症包括5例患者动脉插管部位出现血肿，7例出现远端栓塞，1例出现过敏反应。作者评估了溶栓疗效与血栓闭塞的程度、范围和持续时间的相关性。
