Rodionov S V
Grud Serdechnososudistaia Khir. 1992(7-8):12-7.
Fibrinolytic therapy (FLT) was applied in 79 patients, aged from 37 to 76 years, suffering from thromboses of the main arteries of the pelvis and lower extremities. The duration of the disease ranged from one day to 8 months. FLT was conducted with streptokinase preparations: streptodekase, avelysin, and celiase. FLT lasted 24 hours on average (from 7 hours to 3 days depending on the duration of the disease). The main blood flow in the affected arterial segment was completely restored in 49 (62%) patients. In 30 (38%) cases attempts to restore the blood flow failed. The affected extremity was amputated in 4 patients. Severe hemorrhagic complications occurred in 4%., small subcutaneous hematomas in 14.4%, fragmentation of thrombi with the development of distal embolism in 7.6% of cases, anaphylactic shock developed in one patient. Four patients died.
79例年龄在37至76岁之间、患有骨盆和下肢主要动脉血栓形成的患者接受了纤维蛋白溶解疗法（FLT）。病程从1天到8个月不等。使用链激酶制剂进行FLT治疗：链道酶、阿维溶素和纤溶酶。FLT平均持续24小时（根据病程从7小时至3天不等）。49例（62%）患者受影响动脉段的主要血流完全恢复。30例（38%）恢复血流的尝试失败。4例患者的患侧肢体被截肢。严重出血并发症发生率为4%，小的皮下血肿发生率为14.4%，7.6%的病例出现血栓碎裂并伴有远端栓塞，1例患者发生过敏性休克。4例患者死亡。
