Science. 1962 Nov 16;138(3542):820-2. doi: 10.1126/science.138.3542.820.
When the corneal epithelium of the Chinese hamster is irradiated with ionizing radiation in vivo, a rectilinear relationship is observed between the yield of chromosome aberrations and the dose of x-rays within a dose range of 10 to 150 r. There is no threshold effect for chromosome breakage down to the 10-r level. The mean breakage rate of 0.00352 breaks per cell per roentgen is in very close agreement with the data obtained on other mammalian tissues, both in vitro and in vivo.
当用电离辐射照射中华仓鼠的角膜上皮细胞时，在 10 到 150 拉德的剂量范围内，染色体畸变的产量与 X 射线的剂量之间呈现出直线关系。在 10 拉德的水平以下，不存在染色体断裂的阈值效应。每细胞每伦琴平均断裂率为 0.00352 次，与在体外和体内获得的其他哺乳动物组织的数据非常吻合。
