腕管综合征中滑膜下结缔组织材料特性的评估。
Evaluation of the material properties of the subsynovial connective tissue in carpal tunnel syndrome.
作者信息
Osamura Naoki, Zhao Chunfeng, Zobitz Mark E, An Kai-Nan, Amadio Peter C
机构信息
Biomechanics Laboratory, Division of Orthopedic Research, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, United States.
出版信息
Clin Biomech (Bristol). 2007 Nov;22(9):999-1003. doi: 10.1016/j.clinbiomech.2007.07.009. Epub 2007 Sep 5.
Abstract
BACKGROUND
The purpose of this study was to determine the material properties of the normal carpal tunnel subsynovial connective tissue in response to shear stress.
METHODS
The shear modulus and maximum shear strength were measured with a custom-made micro-tester in 10 specimens of subsynovial connective tissue from 10 wrists in eight patients with idiopathic carpal tunnel syndrome and in 10 specimens from five fresh frozen cadavers without a history of carpal tunnel syndrome.
FINDINGS
The mean shear modulus was 22.8 (SD 15.4)kPa for the patient group and 2.7 (SD 1.8)kPa for the control group. The mean maximum shear strength was 54.6 (SD 20.3)kPa for the patient group and 23.3 (SD 10.7)kPa for the control group. The values for the patient group were significantly higher than the control group (P<0.05).
INTERPRETATION
The material properties of subsynovial connective tissue are altered in patients with idiopathic carpal tunnel syndrome. The impact, if any, of these altered properties on carpal tunnel syndrome remains to be elucidated.
摘要
背景
本研究的目的是确定正常腕管滑膜下结缔组织在剪切应力作用下的材料特性。
方法
使用定制的微型测试仪对8例特发性腕管综合征患者的10个腕关节的滑膜下结缔组织标本以及5具无腕管综合征病史的新鲜冷冻尸体的10个标本进行剪切模量和最大剪切强度测量。
结果
患者组的平均剪切模量为22.8（标准差15.4）kPa，对照组为2.7（标准差1.8）kPa。患者组的平均最大剪切强度为54.6（标准差20.3）kPa，对照组为23.3（标准差10.7）kPa。患者组的值显著高于对照组（P<0.05）。
解读
特发性腕管综合征患者的滑膜下结缔组织材料特性发生改变。这些改变的特性对腕管综合征的影响（如果有的话）仍有待阐明。
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