Saulacic N, Iizuka T, Martin M S, Garcia A G
Department of Cranio-Maxillofacial Surgery, Inselspital, University of Bern, CH-3010 Bern, Switzerland.
Int J Oral Maxillofac Surg. 2008 Jan;37(1):1-7. doi: 10.1016/j.ijom.2007.07.020. Epub 2007 Sep 5.
This literature review was performed to analyse the outcomes of clinical studies of alveolar distraction osteogenesis (DO) listed by PUBMED between January 1996 and December 2006. A PUBMED search identified 128 articles on alveolar DO. Twenty articles covering 209 cases were analysed, considering location, device and procedural parameters, rate of augmentation, aspect of final implant placement and follow up. The mean latency period was 7.26+/-2.31 days, distraction rate 0.71+/-0.27 mm/day, rate of augmentation 6.88+/-2.52 mm and consolidation period 12.22+/-5.58 weeks. A total of 469 implants were placed and followed post loading for an average of 14.19+/-11.03 months, with a survival rate of 97%. Of the different procedural parameters, only the difference between mean consolidation period for failed (8.10+/-2.51 weeks) and successful (12.43+/-5.62 weeks) implants was statistically significant (P=0.01). Use of DO may be advantageous in terms of the success rate of implants placed in augmented sites, but there is still a lack of sufficient data based on long-term follow up. Future experimental studies should evaluate the application of different methods with a view to shortening the overall treatment period and improving the performance of implants placed in distracted alveolar ridges.
本综述旨在分析1996年1月至2006年12月期间PUBMED列出的牙槽骨牵张成骨(DO)临床研究结果。通过PUBMED检索,共识别出128篇关于牙槽骨DO的文章。分析了20篇涵盖209例病例的文章,考虑了部位、器械和操作参数、骨增量率、最终种植体植入情况及随访情况。平均延迟期为7.26±2.31天,牵张速率为0.71±0.27mm/天,骨增量率为6.88±2.52mm,巩固期为12.22±5.58周。共植入469颗种植体,加载后平均随访14.19±11.03个月,生存率为97%。在不同的操作参数中,仅失败种植体(8.10±2.51周)和成功种植体(12.43±5.62周)的平均巩固期差异具有统计学意义(P=0.01)。就植入增量部位的种植体成功率而言,使用DO可能具有优势,但基于长期随访的充分数据仍然缺乏。未来的实验研究应评估不同方法的应用,以缩短总体治疗时间并改善植入牵张后牙槽嵴的种植体性能。