Oliveira M J L, Paiva S M, Martins L H P M, Ramos-Jorge M L, Lima Y B O, Cury J A
Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Caries Res. 2007;41(6):460-6. doi: 10.1159/000107933. Epub 2007 Sep 7.
The aim of the present study was to determine fluoride intake by children at risk of dental fluorosis according to the type of dentifrice used. Forty-two volunteers aged between 20 and 30 months, from 2 kindergartens, were supervised while brushing their teeth with regular dentifrices (nominally 1,500 ppm F) and dentifrices flavoured for children (nominally 1,100 ppm F), brushing 3 times with each type in random order to minimize bias. The amount of fluoride ingested was determined by subtracting the weight of dentifrice recovered from the weight used and calculating the mean of the 3 brushings. Fluoride was analyzed with specific electrodes. Parents were asked how often the children brushed their teeth and the daily tooth brushing frequency was used to calculate the daily fluoride intake. The average fluoride intake using regular dentifrices and those flavoured for children was 0.567 +/- 0.300 and 0.630 +/- 0.320 mg F/day, respectively, corresponding to doses of 0.046 +/- 0.023 and 0.051 +/- 0.026 mg F/kg/day (p > 0.05). Fluoride intake was slightly higher with the use of dentifrices flavoured for children. Moreover, the dose to which children were exposed with either type of dentifrice was very close to that which is considered the limit (0.05-0.07 mg F/kg/day).
本研究的目的是根据所使用的牙膏类型，确定有氟斑牙风险儿童的氟摄入量。来自2所幼儿园的42名年龄在20至30个月之间的志愿者，分别使用普通牙膏（标称含氟量1500 ppm）和儿童口味牙膏（标称含氟量1100 ppm）刷牙，同时受到监督，每种牙膏随机各刷3次以尽量减少偏差。摄入的氟量通过所用牙膏重量减去回收的牙膏重量来确定，并计算3次刷牙的平均值。使用特定电极分析氟含量。询问家长孩子刷牙的频率，并以此计算每日氟摄入量。使用普通牙膏和儿童口味牙膏时，平均氟摄入量分别为0.567±0.300和0.630±0.320毫克氟/天，分别对应于0.046±0.023和0.051±0.026毫克氟/千克/天的剂量（p>0.05）。使用儿童口味牙膏时氟摄入量略高。此外，儿童使用这两种牙膏中的任何一种所接触到的剂量都非常接近被认为的极限值（0.05 - 0.07毫克氟/千克/天）。
