Saviano M, Aida M, Corongiu G
IBM Corporation, Scientific Engineering Computations, Department 48B/MS428, Kingston, New York 12401.
Biopolymers. 1991 Jul;31(8):1017-24. doi: 10.1002/bip.360310811.
The conformation of cyclolinopeptide A [c-(Pro-Pro-Phe-Phe-Leu-Ile-Ile-Leu-Val)], a naturally occurring peptide with remarkable cytoprotective activity, has been investigated by means of molecular dynamics simulations in various molecular environments. Structural and dynamical properties have been analyzed and compared with those experimentally determined. A detailed analysis of hydrogen bonds is reported.
