Gonçales Eduardo Sanches, Rubira-Bullen Izabel Fischer, Rubira Cássia Maria Fischer, Miyazawa Marta, Chinellato Luis Eduardo Montenegro, Consolaro Alberto
Department of Stomatology, Bauru School of Dentistry, University of São Paulo, São Paulo, Brazil.
Quintessence Int. 2007 Sep;38(8):677-80.
Eosinophilic ulcer of the oral mucosa is a benign, rare, self-limiting, and generally asymptomatic lesion that shows spontaneous regression. Its etiopathogenesis is still uncertain, but trauma seems to play a fundamental role in the occurrence of this tumor. Clinically, this lesion manifests as an isolated ulcer preferentially located on the tongue, showing a raised and indurated border in addition to a white or yellowish bed. Microscopically, eosinophilic ulcer is characterized by an inflammatory infiltrate rich in leukocytes. Since these lesions show spontaneous cure, treatment becomes unnecessary, but in certain cases, cure is obtained by excision of the ulcer during biopsy. In these cases, the differential diagnosis with squamous cell carcinoma is made. A case of very small eosinophilic ulcer of the oral mucosa located on the lateral border of the tongue is presented.
口腔黏膜嗜酸性溃疡是一种良性、罕见、自限性且通常无症状的病变，可自发消退。其发病机制尚不确定，但创伤似乎在该肿瘤的发生中起重要作用。临床上，此病变表现为孤立性溃疡，好发于舌部，除白色或淡黄色溃疡底部外，边界隆起且质地硬。显微镜下，嗜酸性溃疡的特征是富含白细胞的炎性浸润。由于这些病变可自发愈合，通常无需治疗，但在某些情况下，活检时切除溃疡可实现治愈。在这些病例中，需与鳞状细胞癌进行鉴别诊断。本文报告一例位于舌外侧缘的极小口腔黏膜嗜酸性溃疡病例。
