从培养的主动脉平滑肌细胞中释放神经生长因子。
Release of nerve growth factor from cultured aortic smooth-muscle cells.
作者信息
Ueyama T, Hamada M, Hano T, Nishio I, Masuyama Y, Ooshima A
机构信息
Department of Medicine, Wakayama Medical College, Japan.
出版信息
Blood Vessels. 1991;28(6):532-6. doi: 10.1159/000158899.
PMID:1782408
Abstract
Conditioned medium from cultured aortic smooth-muscle cells from rat aorta yielded neurite-extending effects on sensory and sympathetic ganglia of chick embryos. These effects were blocked by adding specific antiserum against 2.5S nerve growth factor (NGF), suggesting that NGF might be released from vascular smooth-muscle cells.
摘要
来自大鼠主动脉培养的主动脉平滑肌细胞的条件培养基对鸡胚的感觉和交感神经节产生了神经突延伸效应。通过添加针对2.5S神经生长因子（NGF）的特异性抗血清，这些效应被阻断，这表明NGF可能从血管平滑肌细胞中释放出来。
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