Nasser Sam
Department of Orthopedic Surgery, Wayne State University School of Medicine, Detroit, MI, USA.
Orthopedics. 2007 Aug;30(8 Suppl):89-91.
For many patients, the metals used in contemporary joint replacement surgery produce little or no reaction from the immune system. In a small but significant percentage of patients, however, a very rapid, T cell-mediated, allergic response may occur. If untreated, this reaction may ultimately lead to implant failure. Diagnosis may be complicated, and no effective treatments are available. Fortunately, alternative materials show great promise.
对于许多患者来说，当代关节置换手术中使用的金属对免疫系统几乎没有产生反应或根本不产生反应。然而，在一小部分但数量可观的患者中，可能会发生一种非常迅速的、由T细胞介导的过敏反应。如果不进行治疗，这种反应最终可能导致植入物失效。诊断可能很复杂，而且没有有效的治疗方法。幸运的是，替代材料显示出了巨大的前景。
