Verhoeven G
Laboratory for Experimental Medicine and Endocrinology, Gasthuisberg, Leuven, Belgium.
Bull Assoc Anat (Nancy). 1991 Mar;75(228):167-9.
In the present paper we will briefly review the role of testicular peptides in the interactions between the tubular and the interstitial compartment. Two interactions are discussed in some more detail. 1) It is shown that the effects of FSH on Leydig cell function may be mediated by at least three types of diffusible mediators produced by Sertoli cells: SCF (a 10-30 kD protein), IGF-I and one or more other still unidentified factors. 2) Evidence is presented that some of the effects of androgens on Sertoli cells may be mediated by diffusible factors produced by peritubular cells and that similar or identical mediators are also produced by prostatic stromal cells.
在本文中，我们将简要回顾睾丸肽在曲细精管和间质腔室之间相互作用中的作用。将更详细地讨论两种相互作用。1）研究表明，促卵泡激素（FSH）对睾丸间质细胞功能的影响可能至少由支持细胞产生的三种可扩散介质介导：干细胞因子（SCF，一种10 - 30千道尔顿的蛋白质）、胰岛素样生长因子-I（IGF-I）以及一种或多种其他尚未确定的因子。2）有证据表明，雄激素对支持细胞的某些作用可能由睾丸周细胞产生的可扩散因子介导，并且前列腺基质细胞也产生相似或相同的介质。
