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创伤后的疼痛是创伤后应激障碍的一个风险因素。

Pain in the aftermath of trauma is a risk factor for post-traumatic stress disorder.

作者信息

Norman S B, Stein M B, Dimsdale J E, Hoyt D B

机构信息

Department of Psychiatry, University of California, San Diego, CA 92103, USA.

出版信息

Psychol Med. 2008 Apr;38(4):533-42. doi: 10.1017/S0033291707001389. Epub 2007 Sep 10.

Abstract

BACKGROUND

Identifying risk factors for the development of post-traumatic stress disorder (PTSD) is important for understanding and ultimately preventing the disorder. This study assessed pain shortly after traumatic injury (i.e. peritraumatic pain) as a risk factor for PTSD.

METHOD

Participants (n=115) were patients admitted to a Level 1 Surgical Trauma Center. Admission to this service reflected a severe physical injury requiring specialized, emergent trauma care. Participants completed a pain questionnaire within 48 h of traumatic injury and a PTSD diagnostic module 4 and 8 months later.

RESULTS

Peritraumatic pain was associated with an increased risk of PTSD, even after controlling for a number of other significant risk factors other than acute stress disorder symptoms. An increase of 0.5 s.d. from the mean in a 0-10 pain rating scale 24-48 h after injury was associated with an increased odds of PTSD at 4 months by more than fivefold, and at 8 months by almost sevenfold. A single item regarding amount of pain at the time of hospital admission correctly classified 65% of participants.

CONCLUSIONS

If these findings are replicated in other samples, high levels of peritraumatic pain could be used to identify individuals at elevated risk for PTSD following traumatic injury.

摘要

背景

识别创伤后应激障碍(PTSD)发生的风险因素对于理解并最终预防该疾病至关重要。本研究评估创伤性损伤后不久的疼痛(即创伤周围疼痛)作为PTSD的一个风险因素。

方法

参与者(n = 115)为入住一级外科创伤中心的患者。入住该科室表明存在需要专业紧急创伤护理的严重身体损伤。参与者在创伤性损伤后48小时内完成一份疼痛问卷,并在4个月和8个月后完成一份PTSD诊断模块。

结果

即使在控制了除急性应激障碍症状之外的许多其他重要风险因素后,创伤周围疼痛仍与PTSD风险增加相关。在受伤后24 - 48小时,0 - 10疼痛评分量表上比平均水平增加0.5标准差,与4个月时PTSD几率增加超过五倍以及8个月时增加近七倍相关。关于入院时疼痛程度的单个项目正确分类了65%的参与者。

结论

如果这些发现在其他样本中得到重复,高水平的创伤周围疼痛可用于识别创伤性损伤后PTSD风险升高的个体。

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