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嗅神经胶质囊肿

Olfactory colloid cyst.

作者信息

Alexiou George A, Zigouris Andreas, Pahaturidis Dimitrios, Goussia Ann, Tsiouris Spyridon, Fotopoulos Andreas D, Zagorianakou Panayiota, Voulgaris Spyridon

机构信息

Department of Neurosurgery, University Hospital of Ioannina, Ioannina, Greece.

出版信息

Clin Neurol Neurosurg. 2007 Dec;109(10):902-4. doi: 10.1016/j.clineuro.2007.07.023. Epub 2007 Sep 6.

Abstract

Colloid cysts are rare intracerebral lesions that are predominantly located in the third ventricle. Extraventricular colloid cysts have only rarely been reported but so far there are no reports of a colloid cyst residing in the olfactory groove. A 74-year-old patient underwent a brain computed tomography scan for a mild head trauma that incidentally revealed a space-occupying lesion near the olfactory groove. Brain magnetic resonance imaging that ensued demonstrated a hyperintense lesion in T1, T2, and FLAIR sequences, without evidence of surrounding brain edema. To evaluate the metabolic status of the lesion, brain single-photon emission computed tomography with 99mTc-Tetrofosmin was then performed, revealing no tracer uptake, a finding consistent with benignity. Due to the diagnostic uncertainty the excision of the lesion was proposed. The patient underwent surgery and intraoperative a cyst was revealed. Furthermore the cyst seemed to erode the dura and due to its location there was an imminent danger for cerebrospinal fluid leak. Therefore a repair of the dura was performed and the cyst was excised totally. Histology verified the presence of a colloid cyst. Colloid cysts should be included in the differential diagnosis of lesions in the anterior fossa and although benign they may have an aggressive presentation by eroding the dura and producing CSF leak.

摘要

胶样囊肿是罕见的脑内病变,主要位于第三脑室。脑室外胶样囊肿仅有罕见报道,而迄今为止尚无位于嗅沟的胶样囊肿的报道。一名74岁患者因轻度头部外伤接受脑部计算机断层扫描,偶然发现嗅沟附近有占位性病变。随后的脑部磁共振成像显示在T1、T2和液体衰减反转恢复序列中有一个高信号病变,无周围脑水肿迹象。为评估病变的代谢状态,随后进行了99mTc-替曲膦脑单光子发射计算机断层扫描,未发现示踪剂摄取,这一发现与良性病变相符。由于诊断存在不确定性,建议切除病变。患者接受了手术,术中发现一个囊肿。此外,囊肿似乎侵蚀了硬脑膜,因其位置,存在脑脊液漏的紧迫风险。因此,进行了硬脑膜修补,并将囊肿完全切除。组织学证实为胶样囊肿。胶样囊肿应纳入前颅窝病变的鉴别诊断,尽管为良性,但它们可能通过侵蚀硬脑膜和导致脑脊液漏而呈现侵袭性表现。

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