Tang Yanqing, Wang Fei, Xie Guangrong, Liu Jun, Li Lehua, Su Linyan, Liu Ying, Hu Xian, He Zhong, Blumberg Hilary P
Department of Psychiatry, The Second Xiangya Hospital, Central South University, 86, Mid-Renmin Road, Changsha, Hunan 410011, PR China.
Psychiatry Res. 2007 Oct 15;156(1):83-6. doi: 10.1016/j.pscychresns.2007.03.005. Epub 2007 Sep 6.
High resolution magnetic resonance imaging and voxel-based morphometry were used to compare regional gray matter volumes between 14 medication-naïve female participants with a first episode of major depressive disorder (MDD) and 13 female healthy comparison participants (HC). Volumes of bilateral ventral anterior cingulate cortex (vACC) and right amygdala were significantly smaller in the MDD group than in the HC group. These results suggest that volume reductions in vACC and amygdala in females with MDD are present at illness onset.
使用高分辨率磁共振成像和基于体素的形态测量法，比较了14名首次发作重度抑郁症（MDD）且未接受过药物治疗的女性参与者与13名女性健康对照参与者（HC）之间的区域灰质体积。MDD组双侧腹侧前扣带回皮质（vACC）和右侧杏仁核的体积显著小于HC组。这些结果表明，患有MDD的女性在疾病发作时就存在vACC和杏仁核体积减小的情况。
