Tanaka T, Kondo S, Hori T, Tanaka S, Yonemasu Y
Department of Neurosurgery, Asahikawa Medical College, Japan.
Brain Res. 1991 Sep 13;559(1):154-8. doi: 10.1016/0006-8993(91)90299-b.
Hippocampal degenerative lesions were made bilaterally by means of multiple ibotenic acid injections and development of amygdala kindling was studied. In groups with lesions in either bilateral dorsal or ventral hippocampus, stimulations required for kindling were almost the same as those of controls. In the group with lesion of the entire hippocampus, kindling development was remarkably slow especially in the early stage of the kindling process. However, kindling effect was finally established in all groups.
通过双侧多次注射鹅膏蕈氨酸制造海马体退行性病变，并研究杏仁核点燃的发展情况。在双侧背侧或腹侧海马体有病变的组中，点燃所需的刺激与对照组几乎相同。在整个海马体有病变的组中，点燃发展明显缓慢，尤其是在点燃过程的早期阶段。然而，最终所有组都建立了点燃效应。
