Cain D P, Stewart D J
Department of Psychology, University of Western Ontario, London, Canada.
Pharmacol Biochem Behav. 1990 May;36(1):207-10. doi: 10.1016/0091-3057(90)90152-8.
The effect of ibotenate lesions of septum and substantia innominata on electrical kindling of the amygdala was investigated in rats. The lesions significantly retarded kindling in the absence of a change in initial seizure sensitivity. This suggests that cholinergic neurotransmission can contribute to, but is not crucial for, amygdala kindling, and that a major component of the cholinergic circuitry involved in amygdala kindling may originate in the septum or substantia innominata or both.
研究了大鼠中隔和无名质的鹅膏蕈氨酸损伤对杏仁核电点燃的影响。这些损伤在初始癫痫发作敏感性无变化的情况下显著延缓了点燃。这表明胆碱能神经传递可促进杏仁核电点燃,但并非关键因素,且参与杏仁核电点燃的胆碱能神经回路的主要成分可能起源于中隔或无名质或两者。