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一个用于在外照射放疗中基于等效均匀剂量（EUD）计算正常组织并发症概率（NTCP）和肿瘤控制概率（TCP）的免费程序。

A free program for calculating EUD-based NTCP and TCP in external beam radiotherapy.

作者信息

Gay Hiram A, Niemierko Andrzej

机构信息

Department of Radiation Oncology, The Brody School of Medicine at East Carolina University, 600 Moye Boulevard, Greenville, NC 27834, USA.

出版信息

Phys Med. 2007 Dec;23(3-4):115-25. doi: 10.1016/j.ejmp.2007.07.001. Epub 2007 Sep 7.

DOI:10.1016/j.ejmp.2007.07.001
PMID:17825595
Abstract

PURPOSE

Provide a simple research tool that may be used to calculate the NCTP or TCP of a particular treatment plan. Illustrate the implementation of the EUD-based NTCP and TCP models as a research tool.

METHODS AND MATERIALS

A high-level computing language was chosen to implement Niemierko's EUD-based NTCP and TCP mathematical models. The necessary treatment planning software requirements were clearly defined.

RESULTS

The computer code is presented and explained. Six simple examples were created to quickly troubleshoot the reader's code implementation. A table of model parameters based on the Emami data was generated.

摘要

目的

提供一种简单的研究工具，可用于计算特定治疗计划的正常组织并发症概率（NCTP）或肿瘤控制概率（TCP）。阐明基于等效均匀剂量（EUD）的正常组织并发症概率和肿瘤控制概率模型作为研究工具的应用。

方法和材料

选择一种高级计算语言来实现涅米尔科基于等效均匀剂量的正常组织并发症概率和肿瘤控制概率数学模型。明确界定了必要的治疗计划软件要求。

结果

展示并解释了计算机代码。创建了六个简单示例以快速排查读者代码实现中的问题。生成了基于埃马米数据的模型参数表。

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