Ishikawa Yumi, Uechi Masami, Ishikawa Ryoukichi, Wakao Yoshito, Higuchi Sei-ichi
Ishikawa Animal Hospital, Yokosuka, Kanagawa, Japan.
J Vet Med Sci. 2007 Aug;69(8):869-71. doi: 10.1292/jvms.69.869.
The objective of this study was to evaluate the hemodynamics of the anesthetic isoflurane in healthy cats given angiotensin-converting enzyme inhibitor (ACEI). The 7 healthy young cats and 3 old cats were received placebo or enalapril 0.5 mg/kg orally. The change in systolic arterial pressure from the baseline to 30 min postanesthesia in the ACEI group was significantly higher than in the placebo group (mean +/- SD: -39 +/- 13% vs. -17 +/- 12%, respectively). The present study indicated that general anesthesia may induce hypotension after the administration of an ACEI.
本研究的目的是评估在给予血管紧张素转换酶抑制剂（ACEI）的健康猫中麻醉药异氟烷的血流动力学。7只健康的年轻猫和3只老猫口服接受安慰剂或0.5mg/kg依那普利。ACEI组从基线到麻醉后30分钟收缩压的变化显著高于安慰剂组（平均值±标准差：分别为-39±13% vs. -17±12%）。本研究表明，全身麻醉在给予ACEI后可能诱发低血压。
