Kozlov V S, Shilenkova V V, Derzhavina L L, Kramnoĭ A I
Vestn Otorinolaringol. 2007(4):45-8.
An open, randomized, comparative trial of the drug bioparox was made in 50 patients. Nasal cavity function and its changes in response to bioparox administration were studied with the saccharin test and measurement of ciliary motor activity (CMA) using a special computer program. Significant suppression of the transport function and CMA in all the patients with catarrhal rhinosinusitis was observed. SMA on the inferior turbinated bone and septum was minimal, being low on the middle turbinated bone. After 7 days of bioparox administration mean value of CMA rose 2-fold. Thus, it is demonstrated that bioparox inhalations have no negative effect on nasal ciliated epithelium. On the contrary, it enhances its recovery.
对50名患者进行了药物比奥帕罗克斯的开放性随机对照试验。使用糖精试验和一种特殊的计算机程序测量纤毛运动活性（CMA），研究鼻腔功能及其对比奥帕罗克斯给药的反应变化。观察到所有患卡他性鼻-鼻窦炎的患者的转运功能和CMA均受到显著抑制。下鼻甲和鼻中隔上的纤毛运动活性最低，中鼻甲上的则较低。比奥帕罗克斯给药7天后，CMA的平均值提高了两倍。因此，证明比奥帕罗克斯吸入对鼻纤毛上皮没有负面影响。相反，它能促进其恢复。
