[甲基汞对大鼠胚胎肝细胞染色体的经胎盘效应]
[The transplacental effect of methylmercury on the chromosome of embryo liver cells in rat].
作者信息
Li Y H, Lin X W
机构信息
School of Preventive Medicine, Norman Bethune University of Medical Sciences, Changchun.
出版信息
Zhonghua Yu Fang Yi Xue Za Zhi. 1991 Jul;25(4):220-1.
PMID:1782827
Abstract
The effect of methylmercury on the chromosome of embryo liver cells of rat was studied in vivo. The results showed that the rate of chromosome aberration both of embryo liver cells and maternal bone marrow cells increased linearly with the dose of methylmercury. The linear equations were as follows: Yembryo liver cell = 10.30 + 2.54D (r = 0.9573, P less than 0.01) Ymarrow cell = 2.34 + 0.71D (r = 0.9782, P less than 0.01).
摘要
在体内研究了甲基汞对大鼠胚胎肝细胞染色体的影响。结果表明，胚胎肝细胞和母体骨髓细胞的染色体畸变率均随甲基汞剂量的增加呈线性增加。线性方程如下：胚胎肝细胞Y = 10.30 + 2.54D（r = 0.9573，P＜0.01）；骨髓细胞Y = 2.34 + 0.71D（r = 0.9782，P＜0.01）。
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