Jernberg Elise J N, Moi Harald
Olafiaklinikken, Legevaktsetaten, Oslo kommune, Grensen 5-7, 0159 Oslo.
Tidsskr Nor Laegeforen. 2007 Sep 6;127(17):2233-5.
Non-gonococcal urethritis/cervicitis (NGU) is now the most common sexually transmitted infection that is possible to treat. Mycoplasma genitalium is a microorganism about to be established as an aetiological agent of NGU and upper genital infection.
The article is based on literature identified through a Pubmed search.
There seems to be sufficient evidence to conclude that Mycoplasma genitalium causes sexually transmitted infection. The microbe is associated with non-gonococcal urethritis in both men and women and cervicitis in women. It may also be the cause of upper genital infection in women. M. genitalium seems to cause more severe urethritis and more often lead to symptomatic urethritis/cervicitis than non-chlamydia-non-gonococcal urethritis/cervicitis that is not associated with M. genitalium. For testing, a cervical/vaginal swab should be used for women and first void urine should be collected for both sexes. Nucleic acid amplification tests are used. Azithromycin is more effective against M. genitalium than doxycycline and erythromycin. Moxifloxacin is effective in cases of azithromycin resistance.
非淋菌性尿道炎/宫颈炎（NGU）是目前最常见的可治疗性传播感染。生殖支原体是一种即将被确认为NGU和上生殖道感染病原体的微生物。
本文基于通过PubMed检索确定的文献。
似乎有足够的证据得出结论，生殖支原体可引起性传播感染。这种微生物与男性和女性的非淋菌性尿道炎以及女性的宫颈炎有关。它也可能是女性上生殖道感染的原因。与不伴有生殖支原体的非衣原体 - 非淋菌性尿道炎/宫颈炎相比，生殖支原体似乎会引起更严重的尿道炎，并且更常导致有症状的尿道炎/宫颈炎。检测时，女性应使用宫颈/阴道拭子，男女均应收集首次晨尿。采用核酸扩增检测。阿奇霉素对生殖支原体的疗效优于多西环素和红霉素。莫西沙星对阿奇霉素耐药的病例有效。
