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[手指硬下疳。诊断的曲折之路]

[Chancre of the finger. A circuitous route to diagnosis].

作者信息

Anemüller W, Bräuninger W, Krahl D, Turzynski A, Rose C

机构信息

Klinik für Dermatologie, Allergologie und Venerologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.

出版信息

Hautarzt. 2008 Jun;59(6):499-502. doi: 10.1007/s00105-007-1390-1.

Abstract

A 33-year-old woman presented with a 4-months history of a granulating ulcer on the right index finger. Paronychia was suspected and nail extraction with subsequent histopathologic examination of the removed tissue was performed. Two months later, it became known that the patient's sexual partner had been treated for syphilis. The patient's serology was also positive. Subsequent examination of the original tissue sample by polymerase chain reaction, immunohistochemistry using Treponema pallidum-specific antibodies, and silver staining revealed large numbers of syphilis bacteria, confirming the diagnosis of extragenital chancre.

摘要

一名33岁女性,右手食指出现肉芽性溃疡4个月。怀疑为甲沟炎,遂进行拔甲,并对切除组织进行组织病理学检查。两个月后,得知患者的性伴侣曾接受梅毒治疗。患者的血清学检查也呈阳性。随后对原始组织样本进行聚合酶链反应检测、使用梅毒特异性抗体的免疫组织化学检测以及银染色,结果显示大量梅毒螺旋体,确诊为生殖器外硬下疳。

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