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巴西孕妇中的 Rollet 混合下疳:一个不寻常的病例报告。

Rollet's mixed chancre in Brazilian pregnant women: An unusual case report.

机构信息

Gynecology and Obstetrics Medical Residency Program at UNIMED Vitória, Vitória, Espírito Santo State, Brazil.

Gynecology and Obstetrics Department at Federal University of Espírito Santo, Vitória, Espírito Santo State, Brazil.

出版信息

Int J Infect Dis. 2020 Feb;91:57-59. doi: 10.1016/j.ijid.2019.11.011. Epub 2019 Nov 16.

DOI:10.1016/j.ijid.2019.11.011
PMID:31743797
Abstract

Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum and has shown a significant increase in recent decades. It may be associated with other STIs such as soft chancre or chancroid, which is an uncommon infection in Brazil. The presence of ulcerated genital lesions is associated with a higher risk of HIV transmission. An accurate clinical and laboratory diagnosis of genital ulcer disease is essential for the appropriate treatment of pregnant women, in order to avoid congenital syphilis, a severe complication of mother-to-child vertical transmission. We report the case of a woman in the third trimester of pregnancy with Rollet's mixed chancre and describe the clinical and laboratory diagnosis, as well as the treatment of these diseases in pregnancy. We emphasize the importance of training health professionals on early diagnosis and treatment in order to avoid mother-to-child transmission.

摘要

梅毒是一种由梅毒螺旋体引起的性传播感染(STI),近年来发病率显著上升。它可能与其他性传播感染(如软性下疳或腹股沟横痃)相关,后者在巴西较为少见。生殖器溃疡的存在与 HIV 传播的风险增加相关。准确的临床和实验室诊断对于孕妇的适当治疗至关重要,以避免先天性梅毒,这是母婴垂直传播的一种严重并发症。我们报告了一例妊娠晚期患有 Rollet 混合下疳的女性病例,并描述了其临床和实验室诊断以及妊娠期间的治疗。我们强调了对卫生专业人员进行早期诊断和治疗培训的重要性,以避免母婴传播。

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Rollet's mixed chancre in Brazilian pregnant women: An unusual case report.巴西孕妇中的 Rollet 混合下疳:一个不寻常的病例报告。
Int J Infect Dis. 2020 Feb;91:57-59. doi: 10.1016/j.ijid.2019.11.011. Epub 2019 Nov 16.
2
Rollet's mixed chancre in an adult woman diagnosed in the state of Amazonas, Brazil: A case report.巴西亚马孙州一名成年女性身上诊断出的罗莱特混合性下疳:病例报告。
Int J STD AIDS. 2025 Jul;36(8):667-669. doi: 10.1177/09564624241267133. Epub 2024 Jul 24.
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[Assessment of the congenital syphilis prevention programs].[先天性梅毒预防项目评估]
Rev Med Chir Soc Med Nat Iasi. 2011 Jul-Sep;115(3):934-7.
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National guideline for the management of early syphilis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases).早期梅毒管理国家指南。临床疗效小组(性传播疾病医学协会和泌尿生殖医学协会)
Sex Transm Infect. 1999 Aug;75 Suppl 1:S29-33.
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[Syphilitic chancre in the mouth: an unusual location. Case report].[口腔梅毒硬下疳:一个不寻常的部位。病例报告]
Rev Med Inst Mex Seguro Soc. 2022 Oct 25;60(6):703-707.
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Primary syphilis of the oropharynx: an unusual location of a chancre.口咽部原发性梅毒:一种不寻常部位的硬下疳。
Int J STD AIDS. 2015 Aug;26(9):679-81. doi: 10.1177/0956462414551235. Epub 2014 Sep 4.
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Acta Derm Venereol. 2013 Mar 27;93(2):236-7. doi: 10.2340/00015555-1355.
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Amoxicillin and Ceftriaxone as Treatment Alternatives to Penicillin for Maternal Syphilis.阿莫西林和头孢曲松作为孕产妇梅毒青霉素治疗的替代方案。
Emerg Infect Dis. 2017 May;23(5):827-829. doi: 10.3201/eid2305.161936.
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Acquired syphilis: update on clinical, diagnostic and therapeutic aspects.获得性梅毒:临床、诊断及治疗方面的最新进展
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