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[单纯放疗治疗子宫内膜癌]

[Endometrial carcinoma treated by radiotherapy alone].

作者信息

Sun J H

机构信息

Cancer Institute, Chinese Academy of Medical Sciences, Beijing.

出版信息

Zhonghua Zhong Liu Za Zhi. 1991 Sep;13(5):375-7.

PMID:1782852
Abstract

90 patients with endometrial carcinoma treated from 1958 to 1984 by radiotherapy alone are presented. They constituted 18.7% of all cases of endometrial carcinoma treated in the same period. According to the clinical staging system of FIGO, there were 28.89% Stage Ia, 8.89% Stage Ib, 38.89% Stage II, 20% Stage III and 3.33% Stage IV lesions. In this series, 82 patients suffered from adenocarcinoma and 8 patients from adenoacanthoma. Two treatment regimens were adopted: 1. intracavitary Ra (137Cs or 60Co) as the major form of treatment supplemented by external irradiation in 82 patients (including 5 by intracavitary 137Cs afterloading), 2. external irradiation supplemented by intracavitary Ra (or 137Cs) radiation in 8 patients. The overall 5-year survival rate was 48.89% (Stage I 58.82%, Stage II 51.42%, Stage III 33.3% and Stage IV 0%). Complications were proctitis in 17 cases hematuria in 4 and rectovaginal fistula in 1. The 5 patients treated by intracavitary afterloading radiation with high doses at reference points A and F all survived for more than 5 years. This may imply a bright future for this form of radiotherapy in the treatment of endometrial carcinoma.

摘要

本文报告了1958年至1984年间仅接受放射治疗的90例子宫内膜癌患者。他们占同期治疗的所有子宫内膜癌病例的18.7%。根据国际妇产科联盟(FIGO)的临床分期系统,Ia期病变占28.89%,Ib期占8.89%,II期占38.89%,III期占20%,IV期占3.33%。在这个系列中,82例为腺癌,8例为腺棘癌。采用了两种治疗方案:1. 82例患者以腔内镭(137铯或60钴)作为主要治疗方式,并辅以体外照射(其中5例为腔内137铯后装治疗);2. 8例患者以体外照射为主,辅以腔内镭(或137铯)照射。总体5年生存率为48.89%(I期为58.82%,II期为51.42%,III期为33.3%,IV期为0%)。并发症包括17例直肠炎、4例血尿和1例直肠阴道瘘。5例接受腔内高剂量A点和F点后装放疗的患者均存活超过5年。这可能意味着这种放疗方式在子宫内膜癌治疗方面有着光明的前景。

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