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[正常条件下及动脉粥样硬化发展过程中动脉壁的组织酶学]

[The histoenzymology of arterial walls under normal conditions and during the development of atherosclerosis].

作者信息

Tararak E M, Khmel'nitskaia T O

出版信息

Arkh Patol. 1975;37(11):80-5.

PMID:178294
Abstract

Investigation of enzymes of the vascular wall in atherosclerosis in man and in experiment should include biochemical studies in combination with histochemical control. It is most probable that the total activity of enzymes in the vascular wall in atherosclerosis depends upon the functional state of smooth-muscle cells. The character of changes in the activity of enzymes in the arteries susceptible to atherosclerosis makes it possible to prognose disturbances in metabolism of the vascular wall and partially to explain the sequency of the development of the atherosclerotic process.

摘要

对人类和实验性动脉粥样硬化中血管壁酶的研究应包括结合组织化学对照的生化研究。动脉粥样硬化中血管壁酶的总活性很可能取决于平滑肌细胞的功能状态。易患动脉粥样硬化的动脉中酶活性变化的特征使得预测血管壁代谢紊乱并部分解释动脉粥样硬化过程发展的先后顺序成为可能。

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