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Kinetics of cholinesterase inhibition by eptastigmine in man.

作者信息

Unni L K, Hutt V, Imbimbo B P, Becker R E

出版信息

Eur J Clin Pharmacol. 1991;41(1):83-4. doi: 10.1007/BF00280116.

DOI:10.1007/BF00280116
PMID:1782985
Abstract
摘要

相似文献

1
Kinetics of cholinesterase inhibition by eptastigmine in man.艾斯的明对人体胆碱酯酶抑制作用的动力学
Eur J Clin Pharmacol. 1991;41(1):83-4. doi: 10.1007/BF00280116.
2
Relationship between pharmacodynamic activity and cognitive effects of eptastigmine in patients with Alzheimer's disease. Eptastigmine Study Group.卡巴拉汀在阿尔茨海默病患者中的药效学活性与认知效应之间的关系。卡巴拉汀研究组。
Clin Pharmacol Ther. 1996 Aug;60(2):218-28. doi: 10.1016/S0009-9236(96)90138-1.
3
Relationship between pharmacokinetics and pharmacodynamics of eptastigmine in young healthy volunteers.依替斯的明在年轻健康志愿者体内的药代动力学与药效学之间的关系。
J Clin Pharmacol. 1995 Mar;35(3):285-90. doi: 10.1002/j.1552-4604.1995.tb04060.x.
4
Pharmacodynamics and pharmacokinetics of eptastigmine in elderly subjects.老年受试者中依替卡明的药效学与药代动力学
Eur J Clin Pharmacol. 1993;45(4):373-6. doi: 10.1007/BF00265958.
5
Rapid potentiometric determination of cholinesterases in plasma and red cells: application to eptastigmine monitoring.血浆和红细胞中胆碱酯酶的快速电位测定：在依替膦监测中的应用。
Chem Biol Interact. 1993 Jun;87(1-3):265-8. doi: 10.1016/0009-2797(93)90053-2.
6
Acetylcholinesterase assay may predict cognitive response of Alzheimer patients to eptastigmine treatment.乙酰胆碱酯酶测定可能预测阿尔茨海默病患者对艾斯能治疗的认知反应。
Eur J Clin Pharmacol. 1998 Nov-Dec;54(9-10):809-10. doi: 10.1007/s002280050556.
7
Pharmacodynamic monitoring of eptastigmine in capillary blood.卡巴拉汀在毛细血管血中的药效学监测。
Eur J Clin Pharmacol. 1996;50(5):425-7. doi: 10.1007/s002280050135.
8
Maximum tolerated dose and pharmacodynamics of eptastigmine in elderly healthy volunteers.老年健康志愿者中依他斯的明的最大耐受剂量及药效学
J Clin Pharmacol. 1998 Jul;38(7):610-7. doi: 10.1002/j.1552-4604.1998.tb04467.x.
9
Phenserine and ring C hetero-analogues: drug candidates for the treatment of Alzheimer's disease.苯丝氨酸及C环杂环类似物：治疗阿尔茨海默病的候选药物。
Med Res Rev. 1995 Jan;15(1):3-31. doi: 10.1002/med.2610150103.
10
Effect of food on the absorption of eptastigmine.食物对依他斯的明吸收的影响。
Eur J Clin Pharmacol. 1998 May;54(3):243-7. doi: 10.1007/s002280050453.

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The PI3K/AKT/mTOR signaling pathway inhibitors enhance radiosensitivity in cancer cell lines.PI3K/AKT/mTOR 信号通路抑制剂增强癌细胞系的放射敏感性。
Mol Biol Rep. 2021 Aug;48(8):1-14. doi: 10.1007/s11033-021-06607-3. Epub 2021 Aug 6.
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Understanding the hysteresis loop conundrum in pharmacokinetic/pharmacodynamic relationships.理解药代动力学/药效动力学关系中的滞后环难题。
J Pharm Pharm Sci. 2014;17(1):34-91.
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Eptastigmine: ten years of pharmacology, toxicology, pharmacokinetic, and clinical studies.依替斯的明：十年药理学、毒理学、药代动力学及临床研究

本文引用的文献

1
Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain.阿尔茨海默病和老年痴呆症：基底前脑神经元的丧失。
Science. 1982 Mar 5;215(4537):1237-9. doi: 10.1126/science.7058341.
2
Enhancement of memory processes in Alzheimer's disease with multiple-dose intravenous physostigmine.多剂量静脉注射毒扁豆碱增强阿尔茨海默病患者的记忆过程
Am J Psychiatry. 1982 Nov;139(11):1421-4. doi: 10.1176/ajp.139.11.1421.
3
Anticholinesterase activity of a new carbamate, heptylphysostigmine, in view of its use in patients with Alzheimer-type dementia.
CNS Drug Rev. 2001 Winter;7(4):369-86. doi: 10.1111/j.1527-3458.2001.tb00205.x.
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Some blood biochemistry parameters during the cholinergic treatment of Alzheimer's disease.
Neurosci Behav Physiol. 2001 Jul-Aug;31(4):457-61. doi: 10.1023/a:1010405115973.
5
Cholinesterase inhibitors for the treatment of Alzheimer's disease in the elderly.用于治疗老年人阿尔茨海默病的胆碱酯酶抑制剂。
Drugs Aging. 2000 Feb;16(2):123-38. doi: 10.2165/00002512-200016020-00004.
6
Pharmacodynamics and pharmacokinetics of eptastigmine in elderly subjects.老年受试者中依替卡明的药效学与药代动力学
Eur J Clin Pharmacol. 1993;45(4):373-6. doi: 10.1007/BF00265958.
7
[Relations between specific neurochemical systems and memory: problems posed by dementia of the Alzheimer type].[特定神经化学系统与记忆之间的关系：阿尔茨海默型痴呆引发的问题]
J Psychiatry Neurosci. 1995 Jan;20(1):49-66.
8
Clinical pharmacokinetics of drugs for Alzheimer's disease.用于治疗阿尔茨海默病药物的临床药代动力学
Clin Pharmacokinet. 1995 Aug;29(2):110-29. doi: 10.2165/00003088-199529020-00005.
新型氨基甲酸酯类化合物庚基毒扁豆碱的抗胆碱酯酶活性及其在阿尔茨海默病型痴呆患者中的应用前景
Eur J Biochem. 1986 May 15;157(1):115-20. doi: 10.1111/j.1432-1033.1986.tb09646.x.
4
A long-lasting cholinesterase inhibitor affecting neural and behavioral processes.一种影响神经和行为过程的长效胆碱酯酶抑制剂。
Pharmacol Biochem Behav. 1987 Mar;26(3):625-9. doi: 10.1016/0091-3057(87)90176-6.
5
Physostigmine effects in Alzheimer's disease: relationship to dementia severity.毒扁豆碱在阿尔茨海默病中的作用：与痴呆严重程度的关系。
Life Sci. 1986 Mar 17;38(11):1021-8. doi: 10.1016/0024-3205(86)90236-5.
6
New analogs of physostigmine: alternative drugs for Alzheimer's disease?毒扁豆碱的新类似物：治疗阿尔茨海默病的替代药物？
Life Sci. 1988;43(23):1921-8. doi: 10.1016/s0024-3205(88)80010-9.
7
The effect of heptyl-physostigmine, a new cholinesterase inhibitor, on the central cholinergic system of the rat.新型胆碱酯酶抑制剂庚基毒扁豆碱对大鼠中枢胆碱能系统的作用。
Neurochem Res. 1989 Oct;14(10):971-7. doi: 10.1007/BF00965931.
8
Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type.口服四氢氨基吖啶治疗阿尔茨海默型老年痴呆的长期疗效
N Engl J Med. 1986 Nov 13;315(20):1241-5. doi: 10.1056/NEJM198611133152001.
9
Extraction of physostigmine from biologic fluids and analysis by liquid chromatography with electrochemical detection.
J Pharmacol Methods. 1990 Sep;24(2):137-43. doi: 10.1016/0160-5402(90)90024-f.
10
Diagnosing dementia and its treatable causes.
Geriatrics. 1979 Mar;34(3):79-83, 87-8.